Four letters. Four million times.
A bacterial genome is almost entirely context. A sequencing run returns all of it and ranks none of it.
Escherichia coli reference genome: 4,641,652 bpEnterprise AI
The models, the platforms they run on, and where it matters the instruments underneath them. Four of our own technologies are in deployment, and the same engineers build for clients.
Antimicrobial resistance
Which is why finding one is not the same as explaining why a drug has stopped working.
Sequencing gives you everything an organism is carrying. Millions of letters, all of it at once, none of it ranked. The usual approach is to compare that against a list of the resistance genes somebody has already described. It is fast, and for organisms that have been studied to death it works well.
A bacterial genome is almost entirely context. A sequencing run returns all of it and ranks none of it.
Escherichia coli reference genome: 4,641,652 bpA resistance determinant is often fewer than a thousand bases. Finding it is a search problem. That was solved years ago.
blaNDM-1 coding sequence: 813 bpA gene can sit silent. Truncated. On a plasmid the organism no longer maintains. Presence and phenotype disagree often enough that presence alone cannot be reported as a result.
This is where a catalogue stops.
The model reads context rather than identity. It returns the protein doing the work, and the drug class it defeats.
Output: the protein, and the drug class it defeatsWhat we built
It returns the protein doing the work, and the drug class it defeats.
Not a database match. An attribution, including for proteins that are not in anyone's catalogue yet.
Culture takes days. Our call lands while empiric therapy is still being chosen, which is the moment a broad-spectrum drug usually gets reached for out of caution.
On-premise, in-country, on hardware a laboratory already owns. Patient data does not have to travel for the answer to arrive.
Send isolates you already have phenotypic results for and compare. That is a better test than anything we could write here.
Our own technology
Each started here as a research problem with no customer attached. Each is now a system in production.
The protein defeating the drug, read out of sequencing data.
Read more →PredictionCervical and breast cancer risk, up to three years before it presents. A reason to look sooner, not a diagnosis.
Read more →ImagingCancer detection from diagnostic imaging, reported at 96.4% accuracy against what the radiologists agreed on.
Read more →DentalThree to four weeks of orthodontic planning, returned in a day.
Read more →Planning
And almost none of that month was ever computation.
It was queueing. A case waits for a technician. The technician produces a setup. The clinician reviews it and sends it back. It waits again. Each round trip is a day of work and about a week of calendar. So we put the clinician inside the pipeline rather than at the end of it.
Compute
Scriptics was training models to run on ordinary processors before accelerated compute became the default in this industry.
That discipline stayed. We use accelerators where a workload earns them. What we design out is the assumption, because a system that assumes an accelerator fleet can only be installed where one has been bought. Ours run on hardware the customer already owns, which is how a diagnostic ends up working in a hospital basement rather than only in a cloud region.
Services
Around thirty capabilities, delivered by the engineers and scientists who write the code rather than by a layer above them.
Agentic systems, machine learning, language and vision, and the evaluation work that decides whether any of it is safe to ship.
Read more →02Modernisation, data platforms, DevOps, cybersecurity, embedded systems and cloud rendering.
Read more →03Full-stack engineering, interface design, and proofs of concept built to answer one question.
Read more →04Data engineering, digital forensics, scientific computing and optimisation.
Read more →05Satellite and radar imagery, weather and climate data, spatial analytics and earth observation platforms.
Read more →06Smart contracts, asset tokenisation, permissioned networks and digital identity.
Read more →Industries
The regulatory bar moves between them. The way we validate does not.
Risk, fraud and decisioning systems under audit, and the platforms that carry them.
Clinical and diagnostic systems, built to an intended use and through validation.
Visual inspection, process optimisation and the instruments on the line.
Intelligent behaviour, procedural content and real-time player analytics.
Routing, scheduling and resource allocation as optimisation problems rather than dashboards.
Detection, response and digital forensics across the estate.
Weather and climate pipelines, forecasting and asset intelligence.
Demand, personalisation and the data platforms underneath them.
Climate and catastrophe modelling, claims automation and portfolio analytics.
How we work
The budget, the compute, the regulation, the date. The design follows from those.
And if it does not close, you will hear that before the contract rather than at the second milestone. Most of our work comes from clients who came back, and a project that should never have started ends that.